Concanavalin A-reactive nuclear matrix glycoprotein
نویسندگان
چکیده
منابع مشابه
Changes in concanavalin A-reactive proteins in inflammatory disorders.
Quantitative changes of concanavalin A (Con A)-reactive proteins in serum samples obtained from rats with induced inflammation and from patients with inflammatory and autoimmune diseases were examined by use of lectin blots. Treatment of rats with a single dose of fermented yeast to induce inflammation caused an extensive increase in Con A-reactivity. These changes were time dependent and were ...
متن کاملEffects of concanavalin A on chondrocyte hypertrophy and matrix calcification.
Resting chondrocytes do not usually undergo differentiation to the hypertrophic stage and calcification. However, incubating these cells with concanavalin A resulted in 10-100-fold increases in alkaline phosphatase activity, binding of 1,25(OH)2-vitamin D3, type X collagen synthesis, 45Ca incorporation into insoluble material, and calcium content. On the other hand, other lectins tested (includ...
متن کاملBINDING SITES ON CONCANAVALIN A 399 Concanavalin
Equilibrium dialysis of concanavalin A against methyl c¢-D-mannopyranoside and methyl C¢-D-glucopyranoside conducted at 2 ° in the presence of I M NaC1 showed that concanavalin A is bivalent. A SCATCHARD plot of the data obtained gave straight lines for both sugars with observed association constants (K') of 1. 4. lO 4 1/mole for methyl ,¢-D-mannopyranoside and o.3" IO 4 1/mole for methyl ~¢-D-...
متن کاملThinking about a nuclear matrix.
The possible existence in eukaryotic cells of an internal, non-chromatin nuclear structural framework that facilitates gene readout as a set of spatially concerted reactions has become a popular but controversial theater of investigation. This article endeavors to present a circumspect review of the nuclear matrix concept as we presently know it, framed around two contrasting hypotheses: (1) th...
متن کاملPurification of the Major Concanavalin A-Binding Surface Glycoprotein from Adult Schistosoma mansoni1
Radiolabeled freeze-thaw and detergent-extracted antigens from adult Schistosoma mansoni were fractionated by concanavalin A-Sepharose 4B affinity chromatography to isolate specific surface membrane glycoproteins. SDS-PAGE and ampholine isoelectric focusing of the a-methylmannoside eluate reveal the major component to have a molecular weight of approximately 58,000 and pi value of approximately...
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ژورنال
عنوان ژورنال: Brazilian Journal of Genetics
سال: 1997
ISSN: 0100-8455
DOI: 10.1590/s0100-84551997000400012